It really is tricky to decide what constitutes a normal toxic or lethal dose. Even so, the lethal oral dose of codeine in an Grownup is documented for being while in the variety of 0.
Generally speaking, dose collection for an elderly patient ought to be careful, commonly starting off within the very low stop in the dosing array, reflecting the larger frequency of reduced hepatic, renal or cardiac function, and of concomitant disorder or other drug therapy.
The codeine and promethazine in Promethazine HCl and Codeine Phosphate Oral Remedy might boost the frequency of seizures in people with seizure Ailments, and may enhance the hazard of seizures taking place in other clinical configurations connected with seizures.
Convey to your medical doctor If the cough would not recuperate in five days. Also, notify your health care provider if your issue will get even worse, or if you have a headache that doesn't disappear, fever, or rash. These might be signs and symptoms of a serious healthcare issue and should be checked by a physician.
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Though it can help Lots of individuals, this medication features a risk for abuse and will occasionally trigger habit. This possibility might be increased For those who have a material use condition (for example overuse of or dependancy to medication/Liquor).
Neuroleptic malignant syndrome (NMS) which can lead to Loss of life. Inform you Health care provider instantly For those who have any of the following indications of NMS:
Retail store at area Promethazine codeine syrup temperature from light-weight and moisture. Usually do not retailer in the toilet. Never freeze. Preserve all drugs faraway from children and Animals.
Narcotic analgesics, like codeine, exert their primary effects over the central nervous system and gastrointestinal tract. The analgesic effects of codeine are due to its central action; however, the precise websites of action have not been determined, and also the mechanisms included appear to be rather intricate.
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It's soluble in water and freely soluble in Alcoholic beverages. The molecular body weight is 320.88. Its molecular components is C17H20N2S•HCl, and it's got the following chemical structure.
Problems OF USE: The data With this database is meant to dietary supplement, not substitute for, the experience and judgment of Health care pros. The information is just not intended to address all attainable works by using, Instructions, safety measures, drug interactions or adverse results, nor really should or not it's construed to point that utilization of a specific drug is Secure, acceptable or effective for you or any individual else.
Codeine is understood to be significantly excreted through the kidney, and the potential risk of adverse reactions to this drug might be better in patients with impaired renal function.
Promoting or giving away Promethazine Hydrochloride and Codeine Phosphate Oral Option might harm Many others, and is particularly against the legislation. Convey to your Health care company In case you have at any time abused or been depending on Liquor, prescription medicines or street prescription drugs.